Homo sapiens Protein: LRRTM4
Summary
InnateDB Protein IDBP-295445.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LRRTM4
Protein Name leucine rich repeat transmembrane neuronal 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000386236
InnateDB Gene IDBG-58344 (LRRTM4)
Protein Structure
UniProt Annotation
Function May play a role in the development and maintenance of the vertebrate nervous system. Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in neuronal tissues. {ECO:0000269PubMed:12676565}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0030054 cell junction
GO:0045211 postsynaptic membrane
Protein Structure and Domains
PDB ID
InterPro IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86VH4
PhosphoSite PhosphoSite-Q86VH4
TrEMBL Q9H9T0
UniProt Splice Variant
Entrez Gene 80059
UniGene Hs.285782
RefSeq NP_079269
HUGO HGNC:19411
OMIM 610870
CCDS CCDS46347
HPRD 11288
IMGT
EMBL AC013408 AC013716 AC016758 AC068048 AC068616 AC079117 AC079146 AC079614 AC093650 AK022630 AL353610 AY182030 AY358324 BC017769 BC099738 BC110058
GenPept AAH17769 AAH99738 AAI10059 AAO67551 AAQ88690 BAB14141