Homo sapiens Protein: LRRTM4
Summary
InnateDB Protein IDBP-295449.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LRRTM4
Protein Name leucine rich repeat transmembrane neuronal 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000387297
InnateDB Gene IDBG-58344 (LRRTM4)
Protein Structure
UniProt Annotation
Function May play a role in the development and maintenance of the vertebrate nervous system. Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in neuronal tissues. {ECO:0000269PubMed:12676565}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0030054 cell junction
GO:0045211 postsynaptic membrane
Protein Structure and Domains
PDB ID
InterPro IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86VH4
PhosphoSite PhosphoSite-Q86VH4
TrEMBL C9JM64
UniProt Splice Variant
Entrez Gene 80059
UniGene Hs.285782
RefSeq NP_001128217
HUGO HGNC:19411
OMIM 610870
CCDS CCDS46346
HPRD 11288
IMGT
EMBL AC013408 AC013716 AC016758 AC068048 AC068616 AC079117 AC079146 AC079614 AC093650 AL353610 AY182030 AY358324 BC099738 BC110058
GenPept AAH99738 AAI10059 AAO67551 AAQ88690