InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TBCA

Summary

InnateDB Protein

IDBP-30409.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TBCA

Protein Name

tubulin folding cofactor A

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000369736

InnateDB Gene

IDBG-30407 (TBCA)

Protein Structure

UniProt Annotation

Function

Tubulin-folding protein; involved in the early step of the tubulin folding pathway.

Subcellular Localization

Cytoplasm, cytoskeleton.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.

Experimentally validated
Total	10 [view]
Protein-Protein	9 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0044822	poly(A) RNA binding
GO:0051082	unfolded protein binding
GO:0051087	chaperone binding

Biological Process

GO:0006457	protein folding
GO:0007021	tubulin complex assembly
GO:0007023	post-chaperonin tubulin folding pathway
GO:0044267	cellular protein metabolic process
GO:0051084	'de novo' posttranslational protein folding

Cellular Component

GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005874	microtubule
GO:0015630	microtubule cytoskeleton
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR004226 Tubulin binding cofactor A

PFAM

PF02970

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O75347

PhosphoSite

PhosphoSite-O75347

TrEMBL

Q6FGD7

UniProt Splice Variant

Entrez Gene

6902

UniGene

Hs.663525

RefSeq

NP_004598

HUGO

HGNC:11579

OMIM

610058

CCDS

CCDS4040

HPRD

18166

IMGT

EMBL

AC026717 AC035147 AC108482 AF038952 AK312207 BC018210 BC105285 BT007354 CH471084 CR542170 CR542186

GenPept

AAC39866 AAH18210 AAI05286 AAP36018 BAG35140 CAG46967 CAG46983 EAW95810