Version 5.4
Homo sapiens Protein: COX6C
Summary
InnateDB Protein IDBP-30461.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COX6C
Protein Name cytochrome c oxidase subunit VIc
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000297564
InnateDB Gene IDBG-30459 (COX6C)
Protein Structure
UniProt Annotation
Function This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Subcellular Localization Mitochondrion inner membrane.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 6 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004129 cytochrome-c oxidase activity
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0022904 respiratory electron transport chain
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR004204 Cytochrome c oxidase subunit 6C
PFAM PF02937
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P09669
PhosphoSite PhosphoSite-P09669
TrEMBL A0A024R9B7
UniProt Splice Variant
Entrez Gene 1345
UniGene
RefSeq
HUGO HGNC:2285
OMIM 124090
CCDS CCDS6284
HPRD 00494
IMGT
EMBL AF067636 AF067637 AK311791 BC000187 BT007007 CH471060 X13238
GenPept AAC73061 AAH00187 AAP35653 BAG34734 CAA31624 EAW91791 EAW91792 EAW91793

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca