Homo sapiens Protein: SLC6A2
Summary
InnateDB Protein IDBP-31384.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC6A2
Protein Name solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
Synonyms NAT1; NET; NET1; SLC6A5;
Species Homo sapiens
Ensembl Protein ENSP00000219833
InnateDB Gene IDBG-31382 (SLC6A2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005328 neurotransmitter:sodium symporter activity
GO:0005333 norepinephrine transmembrane transporter activity
GO:0005334 norepinephrine:sodium symporter activity
GO:0005515 protein binding
GO:0008504 monoamine transmembrane transporter activity
GO:0043014 alpha-tubulin binding
GO:0048487 beta-tubulin binding
Biological Process
GO:0006810 transport
GO:0006836 neurotransmitter transport
GO:0007268 synaptic transmission
GO:0015844 monoamine transport
GO:0015874 norepinephrine transport
GO:0042493 response to drug
GO:0048265 response to pain
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043005 neuron projection
GO:0045121 membrane raft
Protein Structure and Domains
PDB ID
InterPro IPR000175 Sodium:neurotransmitter symporter
IPR002435 Sodium:neurotransmitter symporter, noradrenaline
PFAM PF00209
PRINTS PR00176
PR01201
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P23975
PhosphoSite PhosphoSite-P23975
TrEMBL Q9Y6W9
UniProt Splice Variant
Entrez Gene 6530
UniGene Hs.78036
RefSeq NP_001165975
HUGO HGNC:11048
OMIM 163970
CCDS CCDS54011
HPRD 01232
IMGT
EMBL AB022847 AC136621 AK301811 AK312793 CH471092 M65105 X91117 X91118 X91119 X91120 X91121 X91122 X91123 X91124 X91125 X91126 X91127
GenPept AAA59943 BAA82111 BAG35654 BAG63260 CAA62566 CAC39181 EAW82831 EAW82833 EAW82835