Version 5.4
Homo sapiens Protein: PRPF40B
Summary
InnateDB Protein IDBP-31712.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRPF40B
Protein Name PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
Synonyms HYPC;
Species Homo sapiens
Ensembl Protein ENSP00000261897
InnateDB Gene IDBG-31710 (PRPF40B)
Protein Structure
UniProt Annotation
Function May be involved in pre-mRNA splicing. {ECO:0000269PubMed:9700202}.
Subcellular Localization Nucleus speckle {ECO:0000269PubMed:10958656}.
Disease Associations
Tissue Specificity Expressed in the striatum and cortex of the brain (at protein level). Highly expressed in testis, fetal kidney and fetal brain. Moderately expressed in pancreas, skeletal muscle, placenta, brain and heart. Weakly expressed in colon, ileum, ovary, prostate, spleen, kidney and fetal lung. {ECO:0000269PubMed:10958656, ECO:0000269PubMed:9700202}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0016607 nuclear speck
Protein Structure and Domains
PDB ID
InterPro IPR001202 WW domain
IPR002713 FF domain
PFAM PF00397
PF01846
PRINTS
PIRSF
SMART SM00456
SM00441
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NWY9
PhosphoSite PhosphoSite-Q6NWY9
TrEMBL
UniProt Splice Variant
Entrez Gene 25766
UniGene Hs.706827
RefSeq NP_036404
HUGO HGNC:25031
OMIM
CCDS
HPRD 11044
IMGT
EMBL AF049525 AK027117 AK123353 AL137459 AL834216 BC050398 BC067364 CH471111
GenPept AAC27503 AAH50398 AAH67364 BAB15662 CAB70747 CAD38898 EAW58085

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca