InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CUX1

Summary

InnateDB Protein

IDBP-33367.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CUX1

Protein Name

cut-like homeobox 1

Synonyms

CASP; CDP; CDP/Cut; CDP1; Clox; COY1; CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200; p75;

Species

Homo sapiens

Ensembl Protein

ENSP00000292538

InnateDB Gene

IDBG-547448 (CUX1)

Protein Structure

UniProt Annotation

Function

May be involved in intra-Golgi retrograde transport. {ECO:0000269PubMed:15718469}.

Subcellular Localization

Golgi apparatus membrane {ECO:0000269PubMed:12429822}; Single-pass type IV membrane protein {ECO:0000269PubMed:12429822}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	27 [view]
Protein-Protein	27 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003702	RNA polymerase II transcription factor activity
GO:0016564	transcription repressor activity
GO:0030674	protein binding, bridging
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0000301	retrograde transport, vesicle recycling within Golgi
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006810	transport
GO:0006891	intra-Golgi vesicle-mediated transport
GO:0007275	multicellular organismal development
GO:0030324	lung development
GO:0042491	auditory receptor cell differentiation

Cellular Component

GO:0000139	Golgi membrane
GO:0005634	nucleus
GO:0005794	Golgi apparatus
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030173	integral component of Golgi membrane