InnateDB Protein
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IDBP-33552.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NDUFB7
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Protein Name
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NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
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Synonyms
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B18; CI-B18;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000215565
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InnateDB Gene
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IDBG-33550 (NDUFB7)
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Protein Structure
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Function |
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
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Subcellular Localization |
Mitochondrion {ECO:0000269PubMed:21310150}. Mitochondrion inner membrane {ECO:0000305PubMed:21310150}; Peripheral membrane protein {ECO:0000305PubMed:21310150}. Mitochondrion intermembrane space {ECO:0000269PubMed:21310150}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
15
[view]
|
Protein-Protein |
15
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0003954
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NADH dehydrogenase activity
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GO:0008137
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NADH dehydrogenase (ubiquinone) activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR008698
NADH:ubiquinone oxidoreductase, B18 subunit
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PFAM |
PF05676
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P17568
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PhosphoSite |
PhosphoSite-P17568
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
4713
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UniGene |
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RefSeq |
NP_004137
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HUGO |
HGNC:7702
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OMIM |
603842
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CCDS |
CCDS12314
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HPRD |
11957
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IMGT |
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EMBL |
AF112200
AF217091
BC002595
CH471106
CR450354
M33374
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GenPept |
AAA35675
AAF17188
AAF91223
AAH02595
CAG29350
EAW84436
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