InnateDB Protein
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IDBP-34370.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SERGEF
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Protein Name
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secretion regulating guanine nucleotide exchange factor
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000265965
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InnateDB Gene
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IDBG-34368 (SERGEF)
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Protein Structure
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|
Function |
Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.
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Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:10571079}. Nucleus {ECO:0000269PubMed:10571079}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
6
[view]
|
Protein-Protein |
6
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0005087
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Ran guanyl-nucleotide exchange factor activity
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GO:0005515
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protein binding
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000408
Regulator of chromosome condensation, RCC1
IPR009091
Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
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PFAM |
PF00415
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PRINTS |
PR00633
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9UGK8
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PhosphoSite |
PhosphoSite-Q9UGK8
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TrEMBL |
E9PS70
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UniProt Splice Variant |
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Entrez Gene |
26297
|
UniGene |
Hs.32470
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RefSeq |
NP_036271
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HUGO |
HGNC:17499
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OMIM |
606051
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CCDS |
CCDS7828
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HPRD |
06926
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IMGT |
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EMBL |
AC055860
AC124058
AC124078
AJ243950
AJ243951
BC065375
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GenPept |
AAH65375
CAB60832
CAB60833
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