Homo sapiens Protein: GRAP
Summary
InnateDB Protein IDBP-34499.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GRAP
Protein Name GRB2-related adaptor protein
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000284154
InnateDB Gene IDBG-34497 (GRAP)
Protein Structure
UniProt Annotation
Function Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 15 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005070 SH3/SH2 adaptor activity
GO:0005515 protein binding
Biological Process
GO:0007265 Ras protein signal transduction
GO:0007267 cell-cell signaling
GO:0009967 positive regulation of signal transduction
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000980 SH2 domain
IPR001452 SH3 domain
IPR011511 Variant SH3 domain
PFAM PF00017
PF14633
PF00018
PF14604
PF07653
PRINTS PR00401
PR00452
PIRSF
SMART SM00252
SM00326
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q13588
PhosphoSite PhosphoSite-Q13588
TrEMBL K7EKU7
UniProt Splice Variant
Entrez Gene 10750
UniGene Hs.567416
RefSeq NP_006604
HUGO HGNC:4562
OMIM 604330
CCDS CCDS11202
HPRD 05062
IMGT
EMBL AC003957 AC007952 BC035856 BC063035 BT019981 CR541941 CR541966 U52518
GenPept AAC50541 AAH35856 AAH63035 AAV38784 CAG46739 CAG46764