InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BRD4

Summary

InnateDB Protein

IDBP-34504.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BRD4

Protein Name

bromodomain containing 4

Synonyms

CAP; HUNK1; HUNKI; MCAP;

Species

Homo sapiens

Ensembl Protein

ENSP00000353112

InnateDB Gene

IDBG-34500 (BRD4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 103 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	103 [view]
Protein-Protein	83 [view]
Protein-DNA	19 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002039	p53 binding
GO:0003682	chromatin binding
GO:0005515	protein binding
GO:0070577	lysine-acetylated histone binding

Biological Process

GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0006338	chromatin remodeling
GO:0006351	transcription, DNA-templated
GO:0006974	cellular response to DNA damage stimulus
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
GO:0016032	viral process
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0050727	regulation of inflammatory response
GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain
GO:2000002	negative regulation of DNA damage checkpoint