InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NEUROG2

Summary

InnateDB Protein

IDBP-34518.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NEUROG2

Protein Name

neurogenin 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000317333

InnateDB Gene

IDBG-34516 (NEUROG2)

Protein Structure

UniProt Annotation

Function

Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00981}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding
GO:0046983	protein dimerization activity
GO:0070888	E-box binding

Biological Process

GO:0001764	neuron migration
GO:0006351	transcription, DNA-templated
GO:0007411	axon guidance
GO:0021954	central nervous system neuron development
GO:0022008	neurogenesis
GO:0030182	neuron differentiation
GO:0030900	forebrain development
GO:0045165	cell fate commitment
GO:0045666	positive regulation of neuron differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048469	cell maturation
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity