Version 5.4
Homo sapiens Protein: CA7
Summary
InnateDB Protein IDBP-35666.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CA7
Protein Name carbonic anhydrase VII
Synonyms CAVII;
Species Homo sapiens
Ensembl Protein ENSP00000345659
InnateDB Gene IDBG-35664 (CA7)
Protein Structure
UniProt Annotation
Function Reversible hydration of carbon dioxide.
Subcellular Localization Cytoplasm {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006730 one-carbon metabolic process
GO:0015701 bicarbonate transport
GO:0032230 positive regulation of synaptic transmission, GABAergic
GO:0032849 positive regulation of cellular pH reduction
GO:0044281 small molecule metabolic process
GO:2001225 regulation of chloride transport
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR001148 Alpha carbonic anhydrase
PFAM PF00194
PRINTS
PIRSF
SMART SM01057
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P43166
PhosphoSite PhosphoSite-P43166
TrEMBL
UniProt Splice Variant
Entrez Gene 766
UniGene Hs.37014
RefSeq NP_005173
HUGO HGNC:1381
OMIM 114770
CCDS CCDS10821
HPRD 00263
IMGT
EMBL AC004638 AC044802 AY075019 AY075020 BC033865 CH471092 M76420 M76421 M76422 M76423
GenPept AAA51923 AAC23785 AAH33865 AAL78167 AAL78168 EAW83047

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca