InnateDB Protein
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IDBP-35923.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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MAD2L1
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Protein Name
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MAD2 mitotic arrest deficient-like 1 (yeast)
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Synonyms
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HSMAD2; MAD2;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000332295
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InnateDB Gene
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IDBG-35919 (MAD2L1)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 99 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
99
[view]
|
Protein-Protein |
93
[view]
|
Protein-DNA |
6
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
2 [view]
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|
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Molecular Function |
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Biological Process |
GO:0000278
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mitotic cell cycle
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GO:0007093
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mitotic cell cycle checkpoint
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GO:0007094
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mitotic spindle assembly checkpoint
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GO:0031145
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anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
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GO:0042177
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negative regulation of protein catabolic process
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GO:0043066
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negative regulation of apoptotic process
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GO:0045930
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negative regulation of mitotic cell cycle
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GO:0051436
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negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
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GO:0051439
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regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
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GO:0060564
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negative regulation of mitotic anaphase-promoting complex activity
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GO:0090267
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positive regulation of mitotic cell cycle spindle assembly checkpoint
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Cellular Component |
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PDB ID |
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InterPro |
IPR003511
DNA-binding HORMA
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PFAM |
PF02301
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q13257
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PhosphoSite |
PhosphoSite-Q13257
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
4085
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UniGene |
Hs.591697
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RefSeq |
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HUGO |
HGNC:6763
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OMIM |
601467
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CCDS |
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HPRD |
03274
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IMGT |
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EMBL |
AB056160
AC097173
AF202269
AF202270
AF202271
AF202272
AF202273
AF394735
AJ000186
AK223433
AK298228
AK313827
BC000356
BC005945
BC070283
CH471056
U31278
U65410
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GenPept |
AAC50781
AAC52060
AAH00356
AAH05945
AAH70283
AAK38174
AAN74648
AAY40945
BAB63410
BAD97153
BAG36562
BAG60497
CAA03943
EAX05271
EAX05273
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