InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NRCAM

Summary

InnateDB Protein

IDBP-36091.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NRCAM

Protein Name

neuronal cell adhesion molecule

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000368310

InnateDB Gene

IDBG-36081 (NRCAM)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	8 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0030506	ankyrin binding

Biological Process

GO:0001525	angiogenesis
GO:0001764	neuron migration
GO:0007409	axonogenesis
GO:0007411	axon guidance
GO:0007413	axonal fasciculation
GO:0007416	synapse assembly
GO:0007417	central nervous system development
GO:0016337	single organismal cell-cell adhesion
GO:0030516	regulation of axon extension
GO:0045162	clustering of voltage-gated sodium channels
GO:0045666	positive regulation of neuron differentiation

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0009897	external side of plasma membrane
GO:0043005	neuron projection
GO:0043194	axon initial segment

Protein Structure and Domains

PDB ID

InterPro

IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013151 Immunoglobulin

PFAM

PF00041
PF01108
PF07679
PF00047

PRINTS

PIRSF

SMART

SM00408
SM00409
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q92823