InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TUBA8

Summary

InnateDB Protein

IDBP-361249.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TUBA8

Protein Name

tubulin, alpha 8

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000412646

InnateDB Gene

IDBG-1124 (TUBA8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.

Experimentally validated
Total	18 [view]
Protein-Protein	17 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005200	structural constituent of cytoskeleton
GO:0005525	GTP binding

Biological Process

GO:0006184	GTP catabolic process
GO:0007017	microtubule-based process
GO:0051258	protein polymerization

Cellular Component

GO:0005874	microtubule
GO:0043234	protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR000217 Tubulin
IPR002452 Alpha tubulin
IPR002453 Beta tubulin
IPR002967 Delta tubulin
IPR003008 Tubulin/FtsZ, GTPase domain
IPR004057 Epsilon tubulin
IPR008280 Tubulin/FtsZ, C-terminal
IPR018316 Tubulin/FtsZ, 2-layer sandwich domain

PFAM

PF00091
PF03953

PRINTS

PR01161
PR01162
PR01163
PR01224
PR01519

PIRSF

SMART

SM00864
SM00865

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

C9K0S6

UniProt Splice Variant

Entrez Gene

51807

UniGene

Hs.137400

RefSeq

HUGO

HGNC:12410

OMIM

605742

CCDS

HPRD

05763

IMGT

EMBL

AC008079 AC016027

GenPept