InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SMARCA2

Summary

InnateDB Protein

IDBP-361564.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SMARCA2

Protein Name

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

Synonyms

BAF190; BRM; hBRM; hSNF2a; NCBRS; SNF2; SNF2L2; SNF2LA; Sth1p; SWI2;

Species

Homo sapiens

Ensembl Protein

ENSP00000392081

InnateDB Gene

IDBG-44200 (SMARCA2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 143 experimentally validated interaction(s) in this database.
They are also associated with 34 interaction(s) predicted by orthology.

Experimentally validated
Total	143 [view]
Protein-Protein	139 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	34 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005524	ATP binding
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0008152	metabolic process
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005634	nucleus
GO:0043231	intracellular membrane-bounded organelle
GO:0045111	intermediate filament cytoskeleton

Protein Structure and Domains

PDB ID

InterPro

IPR013999 HAS subgroup
IPR014012 Helicase/SANT-associated, DNA binding
IPR014978 Glutamine-Leucine-Glutamine, QLQ

PFAM

PF07529
PF08880

PRINTS

PIRSF

SMART

SM00573
SM00951

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q6LC24

UniProt Splice Variant

Entrez Gene

6595

UniGene

Hs.298990

RefSeq

HUGO

HGNC:11098

OMIM

600014

CCDS

HPRD

02483

IMGT

EMBL

AL138755 AL359076 BC040029 U92832

GenPept

AAB68685 AAH40029