Version 5.4
Homo sapiens Protein: OGG1
Summary
InnateDB Protein IDBP-361760.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OGG1
Protein Name 8-oxoguanine DNA glycosylase
Synonyms HMMH; HOGG1; MUTM; OGH1;
Species Homo sapiens
Ensembl Protein ENSP00000399810
InnateDB Gene IDBG-15945 (OGG1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 12 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003684 damaged DNA binding
GO:0003824 catalytic activity
GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair
GO:0006289 nucleotide-excision repair
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR003265 HhH-GPD domain
IPR011257 DNA glycosylase
IPR012904 8-oxoguanine DNA glycosylase, N-terminal
PFAM PF00730
PF07934
PRINTS
PIRSF
SMART SM00478
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 4968
UniGene Hs.736214
RefSeq
HUGO HGNC:8125
OMIM 601982
CCDS
HPRD 03582
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca