Version 5.4
Homo sapiens Protein: PDZD2
Summary
InnateDB Protein IDBP-363420.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDZD2
Protein Name PDZ domain containing 2
Synonyms AIPC; PAPIN; PDZK3; PIN1;
Species Homo sapiens
Ensembl Protein ENSP00000402033
InnateDB Gene IDBG-14401 (PDZD2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm {ECO:0000269PubMed:11289102}. Endoplasmic reticulum {ECO:0000269PubMed:11289102}. Note=At cell-cell contacts in lung epithelial cells. {ECO:0000250}.Processed PDZ domain-containing protein 2: Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity Isoform 2 is expressed (at protein level) in prostate and many prostate tumors. {ECO:0000269PubMed:11289102}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005911 cell-cell junction
Protein Structure and Domains
PDB ID
InterPro IPR001478 PDZ domain
PFAM PF00595
PF13180
PRINTS
PIRSF
SMART SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O15018
PhosphoSite PhosphoSite-O15018
TrEMBL B4DGS3
UniProt Splice Variant
Entrez Gene 23037
UniGene Hs.481819
RefSeq NP_835260
HUGO HGNC:18486
OMIM 610697
CCDS CCDS34137
HPRD 10142
IMGT
EMBL AB002298 AF338650 AK294741 CH471118
GenPept AAK07661 BAA20760 BAG57884 EAX10775 EAX10778

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca