InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ATG7

Summary

InnateDB Protein

IDBP-363494.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATG7

Protein Name

ATG7 autophagy related 7 homolog (S. cerevisiae)

Synonyms

APG7-LIKE; APG7L; GSA7;

Species

Homo sapiens

Ensembl Protein

ENSP00000412580

InnateDB Gene

IDBG-18704 (ATG7)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 51 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	51 [view]
Protein-Protein	51 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0019778	Atg12 activating enzyme activity
GO:0019779	Atg8 activating enzyme
GO:0042803	protein homodimerization activity

Biological Process

GO:0000422	mitochondrion degradation
GO:0006464	cellular protein modification process
GO:0006497	protein lipidation
GO:0006501	C-terminal protein lipidation
GO:0006914	autophagy
GO:0006995	cellular response to nitrogen starvation
GO:0009267	cellular response to starvation
GO:0010508	positive regulation of autophagy
GO:0015031	protein transport
GO:0016239	positive regulation of macroautophagy
GO:0016567	protein ubiquitination
GO:0030163	protein catabolic process
GO:0031401	positive regulation of protein modification process
GO:0032446	protein modification by small protein conjugation
GO:0034727	piecemeal microautophagy of nucleus
GO:0043065	positive regulation of apoptotic process
GO:0044805	late nucleophagy
GO:0045732	positive regulation of protein catabolic process
GO:0061025	membrane fusion
GO:0071455	cellular response to hyperoxia