InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LPIN1

Summary

InnateDB Protein

IDBP-364259.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LPIN1

Protein Name

lipin 1

Synonyms

PAP1;

Species

Homo sapiens

Ensembl Protein

ENSP00000397908

InnateDB Gene

IDBG-30220 (LPIN1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001085	RNA polymerase II transcription factor binding
GO:0003674	molecular_function
GO:0003713	transcription coactivator activity
GO:0005515	protein binding
GO:0008195	phosphatidate phosphatase activity
GO:0042826	histone deacetylase binding
GO:0042975	peroxisome proliferator activated receptor binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0000266	mitochondrial fission
GO:0006351	transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006629	lipid metabolic process
GO:0006642	triglyceride mobilization
GO:0006644	phospholipid metabolic process
GO:0006646	phosphatidylethanolamine biosynthetic process
GO:0006656	phosphatidylcholine biosynthetic process
GO:0009062	fatty acid catabolic process
GO:0016311	dephosphorylation
GO:0019432	triglyceride biosynthetic process
GO:0031065	positive regulation of histone deacetylation
GO:0031100	organ regeneration
GO:0031529	ruffle organization
GO:0031532	actin cytoskeleton reorganization
GO:0032869	cellular response to insulin stimulus
GO:0044255	cellular lipid metabolic process
GO:0044281	small molecule metabolic process
GO:0045598	regulation of fat cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0046474	glycerophospholipid biosynthetic process
GO:2001141	regulation of RNA biosynthetic process

Cellular Component

GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0005737	cytoplasm
GO:0005789	endoplasmic reticulum membrane
GO:0005829	cytosol
GO:0031965	nuclear membrane