Version 5.4
Homo sapiens Protein: SLC9A3R2
Summary
InnateDB Protein IDBP-364265.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC9A3R2
Protein Name solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
Synonyms E3KARP; NHE3RF2; NHERF-2; NHERF2; OCTS2; SIP-1; SIP1; TKA-1;
Species Homo sapiens
Ensembl Protein ENSP00000402857
InnateDB Gene IDBG-9763 (SLC9A3R2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 71 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 71 [view]
Protein-Protein 71 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008022 protein C-terminus binding
GO:0019902 phosphatase binding
Biological Process
GO:0006461 protein complex assembly
Cellular Component
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0012505 endomembrane system
GO:0016324 apical plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001478 PDZ domain
IPR015098 EBP50, C-terminal
IPR017300 Na(+)/H(+) exchange regulatory cofactor NHE-RF
PFAM PF00595
PF13180
PF09007
PRINTS
PIRSF PIRSF037866
SMART SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q15599
PhosphoSite PhosphoSite-Q15599
TrEMBL
UniProt Splice Variant
Entrez Gene 9351
UniGene Hs.440896
RefSeq NP_004776
HUGO HGNC:11076
OMIM 606553
CCDS CCDS45383
HPRD 05946
IMGT
EMBL AB014460 AB016243 AC005600 AC093513 AF004900 AF035771 BC014513 BC106001 BM920873 CH471112 U82108 Z50150
GenPept AAB53042 AAC34208 AAC52090 AAC63061 AAH14513 AAI06002 BAA32696 BAA33216 CAA90511 EAW85563 EAW85564 EAW85565 EAW85566

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca