InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ICA1

Summary

InnateDB Protein

IDBP-364981.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ICA1

Protein Name

islet cell autoantigen 1, 69kDa

Synonyms

ICA69; ICAp69;

Species

Homo sapiens

Ensembl Protein

ENSP00000403982

InnateDB Gene

IDBG-8551 (ICA1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0019904	protein domain specific binding

Biological Process

GO:0006836

neurotransmitter transport

Cellular Component

GO:0000139	Golgi membrane
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0030054	cell junction
GO:0030658	transport vesicle membrane
GO:0030667	secretory granule membrane
GO:0030672	synaptic vesicle membrane

Protein Structure and Domains

PDB ID

InterPro

IPR006723 Islet cell autoantigen Ica1, C-terminal
IPR010504 Arfaptin homology (AH) domain

PFAM

PF04629
PF06456

PRINTS

PIRSF

SMART

SM01015

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q05084

PhosphoSite

PhosphoSite-Q05084

TrEMBL

Q9UDQ6

UniProt Splice Variant

Entrez Gene

3382

UniGene

Hs.718069

RefSeq

HUGO

HGNC:5343

OMIM

147625

CCDS

HPRD

00971

IMGT

EMBL

AC006042 AC007009 AK292106 CH471073 EU416199 L01100 L21181 U26591 U37183 U71251 U71252 U71253 U71255 U71256 U71257 U71258 U71259 U71260 U71261 U71262 U71263 U71264

GenPept

AAA02564 AAA64927 AAB19033 AAB94738 AAC50935 AAD50515 ACB47390 BAF84795 EAW93610 EAW93617