InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TRPC4

Summary

InnateDB Protein

IDBP-365506.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TRPC4

Protein Name

transient receptor potential cation channel, subfamily C, member 4

Synonyms

HTRP-4; HTRP4; TRP4;

Species

Homo sapiens

Ensembl Protein

ENSP00000410133

InnateDB Gene

IDBG-25292 (TRPC4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	18 [view]
Protein-Protein	18 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005262	calcium channel activity
GO:0005515	protein binding

Biological Process

GO:0006811	ion transport
GO:0055085	transmembrane transport
GO:0070588	calcium ion transmembrane transport

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR002110 Ankyrin repeat
IPR004729 Transient receptor potential channel
IPR005821 Ion transport domain
IPR013555 Transient receptor ion channel domain
IPR020683 Ankyrin repeat-containing domain

PFAM

PF00023
PF13606
PF00520
PF08344
PF11929
PF12796

PRINTS

PR01415

PIRSF

SMART

SM00248

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt