InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: UBE2K

Summary

InnateDB Protein

IDBP-365827.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

UBE2K

Protein Name

ubiquitin-conjugating enzyme E2K

Synonyms

E2-25K; HIP2; HYPG; LIG; UBC1;

Species

Homo sapiens

Ensembl Protein

ENSP00000390483

InnateDB Gene

IDBG-14649 (UBE2K)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 93 experimentally validated interaction(s) in this database.

Experimentally validated
Total	93 [view]
Protein-Protein	90 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016881	acid-amino acid ligase activity
GO:0031625	ubiquitin protein ligase binding
GO:0034450	ubiquitin-ubiquitin ligase activity

Biological Process

GO:0006511	ubiquitin-dependent protein catabolic process
GO:0070936	protein K48-linked ubiquitination

Cellular Component

GO:0005737	cytoplasm
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000608 Ubiquitin-conjugating enzyme, E2
IPR009060 UBA-like
IPR016135 Ubiquitin-conjugating enzyme/RWD-like

PFAM

PF00179

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P61086

PhosphoSite

PhosphoSite-P61086

TrEMBL

UniProt Splice Variant

Entrez Gene

3093

UniGene

Hs.735771

RefSeq

NP_001104582

HUGO

HGNC:4914

OMIM

602846

CCDS

CCDS47043

HPRD

04165

IMGT

EMBL

AB022435 AB022436 AC105287 AC108471 AK291454 AK315524 BC022804 BC050600 BX339118 CH471069 U58522

GenPept

AAC50633 AAH22804 AAH50600 BAA78555 BAA78556 BAF84143 BAG37905 EAW92948