InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BTN3A1

Summary

InnateDB Protein

IDBP-365834.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BTN3A1

Protein Name

butyrophilin, subfamily 3, member A1

Synonyms

BT3.1; BTF5; BTN3.1; CD277;

Species

Homo sapiens

Ensembl Protein

ENSP00000406667

InnateDB Gene

IDBG-69277 (BTN3A1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0045087	innate immune response (InnateDB)
GO:0050663	cytokine secretion
GO:0050798	activated T cell proliferation
GO:0050852	T cell receptor signaling pathway
GO:0072643	interferon-gamma secretion

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001870 B30.2/SPRY domain
IPR003596 Immunoglobulin V-set, subgroup
IPR003599 Immunoglobulin subtype
IPR003877 SPRY domain
IPR003879 Butyrophylin-like
IPR006574 SPRY-associated
IPR007110 Immunoglobulin-like domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR013106 Immunoglobulin V-set domain

PFAM

PF00622
PF13765
PF07686

PRINTS

PR01407

PIRSF

SMART

SM00406
SM00409
SM00449
SM00589

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt