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InnateDB Protein
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IDBP-366077.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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MTRF1
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Protein Name
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mitochondrial translational release factor 1
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Synonyms
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MRF1; MTTRF1; RF1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000399279
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InnateDB Gene
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IDBG-27238 (MTRF1)
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Protein Structure
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| Function |
Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain non-cognate termination stop codons AGG and AGA.
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| Subcellular Localization |
Mitochondrion {ECO:0000269PubMed:17803939}.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
| Experimentally validated |
| Total |
2
[view]
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| Protein-Protein |
1
[view]
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| Protein-DNA |
1
[view]
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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Molecular Function |
| Accession |
GO Term |
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GO:0016149
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translation release factor activity, codon specific
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| Biological Process |
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR005139
Peptide chain release factor
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| PFAM |
PF03462
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| PRINTS |
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| PIRSF |
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| SMART |
SM00937
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-O75570
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| TrEMBL |
X6RFD4
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| UniProt Splice Variant |
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| Entrez Gene |
9617
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| UniGene |
Hs.737057
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| RefSeq |
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| HUGO |
HGNC:7469
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| OMIM |
604601
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| CCDS |
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| HPRD |
06855
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| IMGT |
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| EMBL |
AL354696
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| GenPept |
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Version 5.4