InnateDB Protein
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IDBP-366172.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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AQP4
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Protein Name
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aquaporin 4
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Synonyms
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HMIWC2; MIWC;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000393121
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InnateDB Gene
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IDBG-1836 (AQP4)
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Protein Structure
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Function |
Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
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Subcellular Localization |
Membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
Brain - muscle >> heart, kidney, lung, and trachea.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
2
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000425
Major intrinsic protein
IPR023271
Aquaporin-like
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PFAM |
PF00230
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PRINTS |
PR00783
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PIRSF |
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SMART |
|
TIGRFAMs |
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Modification |
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SwissProt |
P55087
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PhosphoSite |
PhosphoSite-P55087
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
361
|
UniGene |
Hs.593410
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RefSeq |
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HUGO |
HGNC:637
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OMIM |
600308
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CCDS |
CCDS58617
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HPRD |
02631
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IMGT |
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EMBL |
AC018371
BC022286
D63412
U34845
U34846
U63622
U63623
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GenPept |
AAB26957
AAB26958
AAC50284
AAC52112
AAH22286
BAA09715
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