Version 5.4
Homo sapiens Protein: SYTL5
Summary
InnateDB Protein IDBP-367028.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYTL5
Protein Name synaptotagmin-like 5
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000395220
InnateDB Gene IDBG-56021 (SYTL5)
Protein Structure
UniProt Annotation
Function May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids.
Subcellular Localization Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Highly expressed in placenta and liver.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017137 Rab GTPase binding
GO:0046872 metal ion binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006887 exocytosis
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR000008 C2 domain
IPR010911 Zinc finger, FYVE-type
IPR011011 Zinc finger, FYVE/PHD-type
PFAM PF00168
PF02318
PRINTS PR00360
PIRSF
SMART SM00239
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8TDW5
PhosphoSite PhosphoSite-Q8TDW5
TrEMBL
UniProt Splice Variant
Entrez Gene 94122
UniGene Hs.662334
RefSeq NP_001156806
HUGO HGNC:15589
OMIM
CCDS CCDS55399
HPRD 06736
IMGT
EMBL AB080222 AL121578 BC131585
GenPept AAI31586 BAB88906

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca