Version 5.4
Homo sapiens Gene: SYTL5
Summary
InnateDB Gene IDBG-56021.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYTL5
Gene Name synaptotagmin-like 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000147041
Encoded Proteins
IDBP-56023
synaptotagmin-like 5
IDBP-367028
synaptotagmin-like 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the synaptotagmin-like (Slp) protein family, which contains a unique homology domain at the N-terminus, referred to as the Slp homology domain (SHD). The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of this gene is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:38006582-38128819
Strand Forward strand
Band p11.4
Transcripts
ENST00000297875 ENSP00000297875
ENST00000456733 ENSP00000395220
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017137 Rab GTPase binding
GO:0046872 metal ion binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006887 exocytosis
Cellular Component
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000054453
View Gene Order
ENSBTAG00000004955
Not yet available
Cross-References
SwissProt Q8TDW5
TrEMBL
UniProt Splice Variant
Entrez Gene 94122
UniGene Hs.625148 Hs.662334
RefSeq NM_001163334 NM_001163335 NM_138780
HUGO HGNC:15589
OMIM
CCDS CCDS55399 CCDS14244
HPRD 06736
IMGT
EMBL AB080222 AL121578 BC131585
GenPept AAI31586 BAB88906
RNA Seq Atlas 94122

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca