Version 5.4
| Homo sapiens Protein: COL22A1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-36791.5 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | COL22A1 | ||||||||
| Protein Name | collagen, type XXII, alpha 1 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000303153 | ||||||||
| InnateDB Gene | IDBG-36789 (COL22A1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Acts as a cell adhesion ligand for skin epithelial cells and fibroblasts. | ||||||||
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. Cytoplasm {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Restrictive expression is observed at tissue junctions such as the myotendinous junction in skeletal and heart muscle, the articular cartilage-synovial fluid junction, or the border between the anagen hair follicle and the dermis in the skin. It is deposited in the basement membrane zone of the myotendinous junction and the hair follicle and associated with the extrafibrillar matrix in cartilage. {ECO:0000269PubMed:15016833}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR001791
Laminin G domain IPR002035 von Willebrand factor, type A IPR008160 Collagen triple helix repeat IPR008985 Concanavalin A-like lectin/glucanases superfamily |
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| PFAM |
PF00054
PF02210 PF00092 PF01391 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00210
SM00282 SM00327 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8NFW1 | ||||||||
| PhosphoSite | PhosphoSite-Q8NFW1 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 169044 | ||||||||
| UniGene | Hs.734653 | ||||||||
| RefSeq | NP_690848 | ||||||||
| HUGO | HGNC:22989 | ||||||||
| OMIM | 610026 | ||||||||
| CCDS | CCDS6376 | ||||||||
| HPRD | 09885 | ||||||||
| IMGT | |||||||||
| EMBL | AC068476 AC105130 AC115720 AF406780 AP006262 BC042075 BC144535 | ||||||||
| GenPept | AAH42075 AAI44536 AAN03620 | ||||||||