Version 5.4
Homo sapiens Protein: ATP5S
Summary
InnateDB Protein IDBP-367940.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATP5S
Protein Name ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000389246
InnateDB Gene IDBG-5967 (ATP5S)
Protein Structure
UniProt Annotation
Function Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion {ECO:0000250}. Mitochondrion inner membrane {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015078 hydrogen ion transmembrane transporter activity
GO:0046872 metal ion binding
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015992 proton transport
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99766
PhosphoSite PhosphoSite-Q99766
TrEMBL
UniProt Splice Variant
Entrez Gene 27109
UniGene Hs.656689
RefSeq NP_056499
HUGO HGNC:18799
OMIM
CCDS CCDS45102
HPRD 12503
IMGT
EMBL AK290008 AL359397 AY052377 BC011549 CH471078 U79253
GenPept AAB50202 AAH11549 AAL13058 BAF82697 EAW65718 EAW65722

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca