Version 5.4
Homo sapiens Protein: UBA1
Summary
InnateDB Protein IDBP-369069.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UBA1
Protein Name ubiquitin-like modifier activating enzyme 1
Synonyms A1S9; A1S9T; A1ST; AMCX1; CFAP124; GXP1; POC20; SMAX2; UBA1A; UBE1; UBE1X;
Species Homo sapiens
Ensembl Protein ENSP00000415033
InnateDB Gene IDBG-60053 (UBA1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 177 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 177 [view]
Protein-Protein 176 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0008641 small protein activating enzyme activity
Biological Process
GO:0006464 cellular protein modification process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000011 Ubiquitin/SUMO-activating enzyme E1
IPR000594 UBA/THIF-type NAD/FAD binding fold
IPR009036 Molybdenum cofactor biosynthesis, MoeB
PFAM PF00899
PRINTS PR01849
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5JRR9
UniProt Splice Variant
Entrez Gene 7317
UniGene Hs.533273
RefSeq
HUGO HGNC:12469
OMIM 314370
CCDS
HPRD 02440
IMGT
EMBL AL513366
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca