Version 5.4
Homo sapiens Protein: EXOC5
Summary
InnateDB Protein IDBP-370268.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EXOC5
Protein Name exocyst complex component 5
Synonyms HSEC10; PRO1912; SEC10; SEC10L1; SEC10P;
Species Homo sapiens
Ensembl Protein ENSP00000389934
InnateDB Gene IDBG-7587 (EXOC5)
Protein Structure
UniProt Annotation
Function Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:9119050}.
Disease Associations
Tissue Specificity Ubiquitous. {ECO:0000269PubMed:9119050}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 24 [view]
Protein-Protein 22 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006887 exocytosis
GO:0006892 post-Golgi vesicle-mediated transport
GO:0015031 protein transport
GO:0044267 cellular protein metabolic process
GO:0048278 vesicle docking
GO:0061024 membrane organization
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR009976 Exocyst complex component Sec10-like
PFAM PF07393
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O00471
PhosphoSite PhosphoSite-O00471
TrEMBL G3V4Z7
UniProt Splice Variant
Entrez Gene 10640
UniGene Hs.741807
RefSeq
HUGO HGNC:10696
OMIM 604469
CCDS
HPRD 07258
IMGT
EMBL AK312523 AL139195 AL391152 CH471061 U85946
GenPept AAB53388 BAG35422 EAW80699

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca