InnateDB Protein
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IDBP-370302.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GPN1
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Protein Name
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GPN-loop GTPase 1
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Synonyms
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ATPBD1A; MBDIN; NTPBP; RPAP4; XAB1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000412170
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InnateDB Gene
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IDBG-40039 (GPN1)
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Protein Structure
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Function |
Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA. {ECO:0000269PubMed:17643375}.
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Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:11058119}.
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Disease Associations |
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Tissue Specificity |
Expressed ubiquitously.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 58 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
58
[view]
|
Protein-Protein |
58
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000795
Elongation factor, GTP-binding domain
IPR004130
Uncharacterised protein family, ATP binding
IPR027417
P-loop containing nucleoside triphosphate hydrolase
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PFAM |
PF00009
PF03029
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PRINTS |
PR00315
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9HCN4
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PhosphoSite |
PhosphoSite-Q9HCN4
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
11321
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UniGene |
Hs.731951
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RefSeq |
NP_001138521
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HUGO |
HGNC:17030
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OMIM |
611479
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CCDS |
CCDS46249
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HPRD |
10308
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IMGT |
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EMBL |
AB044661
AC074091
AJ010842
AK298827
AK298866
AK302131
AK310340
AK316404
BC007451
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GenPept |
AAH07451
BAB17612
BAG60957
BAG60986
BAG63506
BAH14775
CAA09376
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