Version 5.4
Homo sapiens Gene: GPN1
Summary
InnateDB Gene IDBG-40039.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPN1
Gene Name GPN-loop GTPase 1
Synonyms ATPBD1A; MBDIN; NTPBP; RPAP4; XAB1
Species Homo sapiens
Ensembl Gene ENSG00000198522
Encoded Proteins
IDBP-40238
GPN-loop GTPase 1
IDBP-294385
GPN-loop GTPase 1
IDBP-370296
GPN-loop GTPase 1
IDBP-370302
GPN-loop GTPase 1
IDBP-370305
GPN-loop GTPase 1
IDBP-485004
GPN-loop GTPase 1
IDBP-484035
GPN-loop GTPase 1
IDBP-808713
GPN-loop GTPase 1
IDBP-808717
GPN-loop GTPase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a guanosine triphosphatase enzyme. The encoded protein may play a role in DNA repair and may function in activation of transcription. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:27628247-27651508
Strand Forward strand
Band p23.3
Transcripts
ENST00000264718 ENSP00000264718
ENST00000407583 ENSP00000384255
ENST00000424214 ENSP00000398115
ENST00000458167 ENSP00000412170
ENST00000436280 ENSP00000395981
ENST00000481754
ENST00000515877 ENSP00000424678
ENST00000503738 ENSP00000427269
ENST00000478484
ENST00000461249
ENST00000610189 ENSP00000476446
ENST00000616939 ENSP00000484680
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 58 experimentally validated interaction(s) in this database.
Experimentally validated
Total 58 [view]
Protein-Protein 58 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000064037
View Gene Order
ENSBTAG00000003904
Not yet available
Cross-References
SwissProt
TrEMBL Q53RZ9
UniProt Splice Variant
Entrez Gene 11321
UniGene
RefSeq NM_007266 NM_001145047 NM_001145048 NM_001145049
HUGO HGNC:17030
OMIM 611479
CCDS CCDS1760 CCDS46248 CCDS46249 CCDS46250
HPRD
IMGT
EMBL AB044661 AC074091 AJ010842 AK298827 AK298866 AK302131 AK310340 AK312992 AK316404 BC007451 CH471053
GenPept AAH07451 AAX93201 BAB17612 BAG35829 BAG60957 BAG60986 BAG63506 BAH14775 CAA09376 EAX00558
RNA Seq Atlas 11321

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca