Version 5.4
Homo sapiens Protein: BCL2L1
Summary
InnateDB Protein IDBP-370484.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BCL2L1
Protein Name BCL2-like 1
Synonyms Bcl-X; bcl-xL; BCL-XL/S; bcl-xS; BCL2L; BCLX; BCLXL; BCLXS; PPP1R52;
Species Homo sapiens
Ensembl Protein ENSP00000411252
InnateDB Gene IDBG-63673 (BCL2L1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 177 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 177 [view]
Protein-Protein 173 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 2 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0042981 regulation of apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro IPR002475 Bcl2-like
IPR003093 Apoptosis regulator, Bcl-2 protein, BH4
IPR013279 Apoptosis regulator, Bcl-X
IPR026298 Blc2 family
PFAM PF02180
PF00452
PRINTS PR01864
PR01862
PIRSF
SMART SM00265
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9H1R6
UniProt Splice Variant
Entrez Gene 598
UniGene Hs.516966
RefSeq
HUGO HGNC:992
OMIM 600039
CCDS
HPRD 02497
IMGT
EMBL AL117381 AL160175
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca