InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ADARB1

Summary

InnateDB Protein

IDBP-370817.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ADARB1

Protein Name

adenosine deaminase, RNA-specific, B1

Synonyms

ADAR2; DRABA2; DRADA2; RED1;

Species

Homo sapiens

Ensembl Protein

ENSP00000414600

InnateDB Gene

IDBG-5701 (ADARB1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003725	double-stranded RNA binding
GO:0003726	double-stranded RNA adenosine deaminase activity
GO:0003729	mRNA binding
GO:0004000	adenosine deaminase activity
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006382	adenosine to inosine editing
GO:0006396	RNA processing
GO:0006397	mRNA processing
GO:0008285	negative regulation of cell proliferation
GO:0010467	gene expression
GO:0016553	base conversion or substitution editing
GO:0016556	mRNA modification
GO:0030336	negative regulation of cell migration
GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0045070	positive regulation of viral genome replication
GO:0045087	innate immune response
GO:0051607	defense response to virus
GO:0051726	regulation of cell cycle