Homo sapiens Protein: MPP7
Summary
InnateDB Protein IDBP-371198.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MPP7
Protein Name membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000398319
InnateDB Gene IDBG-65436 (MPP7)
Protein Structure
UniProt Annotation
Function Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact. {ECO:0000269PubMed:17332497}.
Subcellular Localization Membrane; Peripheral membrane protein. Cell junction, tight junction. Cell junction, adherens junction.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR004172 L27
IPR008144 Guanylate kinase-like
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR014775 L27, C-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00625
PF02828
PRINTS
PIRSF
SMART SM00569
SM00072
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q5T2T1
TrEMBL U5GXS2
UniProt Splice Variant
Entrez Gene 143098
UniGene Hs.499159
RefSeq
HUGO HGNC:26542
OMIM 610973
CCDS
HPRD 14733
IMGT
EMBL AC022021 AL355501 AL390866 AL391423
GenPept