Homo sapiens Protein: SLC30A6
Summary
InnateDB Protein IDBP-371820.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC30A6
Protein Name solute carrier family 30 (zinc transporter), member 6
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000399005
InnateDB Gene IDBG-43344 (SLC30A6)
Protein Structure
UniProt Annotation
Function Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment. {ECO:0000250}.
Subcellular Localization Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Found in vesicles. {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in brain; especially in cerebellum, hippocampus, parahippocampal gyrus, superior and middle temporal gyrus. Also expressed in B-cells, colon, eye, and lung. Lower expression was present in bone, brain, cervix, ear, heart, kidney, muscle, nerve, pancreas, prostate, skin, stomach, and testis. {ECO:0000269PubMed:15154973, ECO:0000269PubMed:16580781}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008324 cation transmembrane transporter activity
Biological Process
GO:0006812 cation transport
GO:0044267 cellular protein metabolic process
GO:0055085 transmembrane transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002524 Cation efflux protein
PFAM PF01545
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NXT4
PhosphoSite PhosphoSite-Q6NXT4
TrEMBL
UniProt Splice Variant
Entrez Gene 55676
UniGene Hs.643379
RefSeq NP_001180443
HUGO HGNC:19305
OMIM 611148
CCDS CCDS54342
HPRD 15368
IMGT
EMBL AK055663 AK304225 AL121653 AL121658 BC032525 BC066903 CH471053 EF560719 EF560726
GenPept AAH32525 AAH66903 ABQ59029 ABQ59036 BAB70980 BAH14137 EAX00456