Version 5.4
Homo sapiens Gene: SLC30A6
Summary
InnateDB Gene IDBG-43344.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC30A6
Gene Name solute carrier family 30 (zinc transporter), member 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000152683
Encoded Proteins
IDBP-43346
solute carrier family 30 (zinc transporter), member 6
IDBP-43348
solute carrier family 30 (zinc transporter), member 6
IDBP-60116
solute carrier family 30 (zinc transporter), member 6
IDBP-294186
solute carrier family 30 (zinc transporter), member 6
IDBP-371820
solute carrier family 30 (zinc transporter), member 6
IDBP-371821
solute carrier family 30 (zinc transporter), member 6
IDBP-371828
solute carrier family 30 (zinc transporter), member 6
IDBP-371831
solute carrier family 30 (zinc transporter), member 6
IDBP-371837
solute carrier family 30 (zinc transporter), member 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A6, permit cellular efflux of zinc (Seve et al., 2004 [PubMed 15154973]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:32165841-32224379
Strand Forward strand
Band p22.3
Transcripts
ENST00000379343 ENSP00000368648
ENST00000282587 ENSP00000282587
ENST00000357055 ENSP00000349563
ENST00000406369 ENSP00000384041
ENST00000435660 ENSP00000399005
ENST00000449777 ENSP00000388013
ENST00000454324 ENSP00000415790
ENST00000440718 ENSP00000393946
ENST00000457724 ENSP00000396634
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005385 zinc ion transmembrane transporter activity
GO:0008324 cation transmembrane transporter activity
Biological Process
GO:0006812 cation transport
GO:0006829 zinc ion transport
GO:0006895 Golgi to endosome transport
GO:0044267 cellular protein metabolic process
GO:0055085 transmembrane transport
GO:0071577 zinc ion transmembrane transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024069
View Gene Order
ENSBTAG00000010898
Not yet available
Pathways
NETPATH
REACTOME
REACT_20582
Zinc efflux and compartmentalization by the SLC30 family pathway
REACT_20547
Metal ion SLC transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_15550
Insulin processing pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_17015
Metabolism of proteins pathway
REACT_20530
Zinc transporters pathway
REACT_160078
Peptide hormone metabolism pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.23248 Hs.643379
RefSeq NM_001193513 NM_001193514 NM_001193515 NM_017964 XM_006712047 XM_006712048
HUGO
OMIM
CCDS CCDS1780 CCDS54341 CCDS54342 CCDS54343
HPRD 15368
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca