Version 5.4
Homo sapiens Protein: SCARB2
Summary
InnateDB Protein IDBP-372016.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCARB2
Protein Name scavenger receptor class B, member 2
Synonyms AMRF; CD36L2; EPM4; HLGP85; LGP85; LIMP-2; LIMPII; SR-BII;
Species Homo sapiens
Ensembl Protein ENSP00000399154
InnateDB Gene IDBG-25361 (SCARB2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0019899 enzyme binding
Biological Process
GO:0006622 protein targeting to lysosome
GO:0007155 cell adhesion
Cellular Component
GO:0005765 lysosomal membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043202 lysosomal lumen
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002159 CD36 antigen
IPR005429 Lysosome membrane protein II
IPR012340 Nucleic acid-binding, OB-fold
PFAM PF01130
PRINTS PR01609
PR01611
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14108
PhosphoSite PhosphoSite-Q14108
TrEMBL
UniProt Splice Variant
Entrez Gene 950
UniGene Hs.599033
RefSeq NP_001191184
HUGO HGNC:1665
OMIM 602257
CCDS CCDS56335
HPRD 03772
IMGT
EMBL AC034139 AC110795 AK296519 AK313016 BC021892 BT006939 CH471057 D12676
GenPept AAH21892 AAP35585 BAA02177 BAG35851 BAG59150 EAX05779

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca