InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CAPZB

Summary

InnateDB Protein

IDBP-373399.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CAPZB

Protein Name

capping protein (actin filament) muscle Z-line, beta

Synonyms

CAPB; CAPPB; CAPZ;

Species

Homo sapiens

Ensembl Protein

ENSP00000401010

InnateDB Gene

IDBG-92609 (CAPZB)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 51 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	51 [view]
Protein-Protein	51 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005515	protein binding
GO:0048487	beta-tubulin binding
GO:0051015	actin filament binding

Biological Process

GO:0030030	cell projection organization
GO:0030032	lamellipodium assembly
GO:0030036	actin cytoskeleton organization
GO:0031115	negative regulation of microtubule polymerization
GO:0031175	neuron projection development
GO:0048747	muscle fiber development
GO:0051016	barbed-end actin filament capping
GO:0090036	regulation of protein kinase C signaling

Cellular Component

GO:0001669	acrosomal vesicle
GO:0008290	F-actin capping protein complex
GO:0014704	intercalated disc
GO:0016020	membrane
GO:0030018	Z disc
GO:0030027	lamellipodium
GO:0030863	cortical cytoskeleton
GO:0071203	WASH complex