InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RPL23A

Summary

InnateDB Protein

IDBP-373955.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPL23A

Protein Name

ribosomal protein L23a

Synonyms

L23A; MDA20;

Species

Homo sapiens

Ensembl Protein

ENSP00000389103

InnateDB Gene

IDBG-37482 (RPL23A)

Protein Structure

UniProt Annotation

Function

This protein binds to a specific region on the 26S rRNA. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 153 experimentally validated interaction(s) in this database.

Experimentally validated
Total	153 [view]
Protein-Protein	152 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0019843	rRNA binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0008283	cell proliferation
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0031932	TORC2 complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR005633 Ribosomal protein L23/L25, N-terminal
IPR012678 Ribosomal protein L23/L15e core domain
IPR013025 Ribosomal protein L25/L23
IPR019985 Ribosomal protein L23

PFAM

PF03939
PF00276

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P62750

PhosphoSite