Version 5.4
Homo sapiens Protein: KIF27
Summary
InnateDB Protein IDBP-374108.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KIF27
Protein Name kinesin family member 27
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000401688
InnateDB Gene IDBG-73799 (KIF27)
Protein Structure
UniProt Annotation
Function Plays an essential role in motile ciliogenesis. {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000305}. Cell projection, cilium {ECO:0000250}. Note=Localizes to centrioles and basal bodies. {ECO:0000250}.
Disease Associations
Tissue Specificity Testis, pancreatic islet, germ cell tumors and Jurkat T-cells.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
GO:0042384 cilium assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005871 kinesin complex
GO:0005874 microtubule
GO:0005929 cilium
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001752 Kinesin, motor domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00225
PRINTS PR00380
PIRSF
SMART SM00129
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86VH2
PhosphoSite PhosphoSite-Q86VH2
TrEMBL B4DMY5
UniProt Splice Variant
Entrez Gene 55582
UniGene Hs.697514
RefSeq NP_001258856
HUGO HGNC:18632
OMIM 611253
CCDS CCDS65071
HPRD 11179
IMGT
EMBL AK297689 AL133654 AL354733 AY237536 AY237537 AY237538 BC140788
GenPept AAI40789 AAP04413 AAP04414 AAP04415 BAG60047 CAB63770 CAI16012 CAI16013

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca