InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TOM1

Summary

InnateDB Protein

IDBP-374151.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TOM1

Protein Name

target of myb1 (chicken)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000413697

InnateDB Gene

IDBG-5330 (TOM1)

Protein Structure

UniProt Annotation

Function

May be involved in intracellular trafficking. Probable association with membranes.

Subcellular Localization

Cytoplasm {ECO:0000305}. Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Widely expressed. Highly expressed in skeletal muscle, heart, placenta and liver. {ECO:0000269PubMed:10329004}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	40 [view]
Protein-Protein	38 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0030276	clathrin binding

Biological Process

GO:0006886	intracellular protein transport
GO:0006897	endocytosis
GO:0015031	protein transport
GO:0016197	endosomal transport

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0005768	endosome
GO:0005769	early endosome
GO:0005829	cytosol
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome