Homo sapiens Protein: HOXC6
Summary
InnateDB Protein IDBP-37418.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HOXC6
Protein Name homeobox C6
Synonyms CP25; HHO.C8; HOX3; HOX3C;
Species Homo sapiens
Ensembl Protein ENSP00000243108
InnateDB Gene IDBG-37416 (HOXC6)
Protein Structure
UniProt Annotation
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003714 transcription corepressor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0007275 multicellular organismal development
GO:0009952 anterior/posterior pattern specification
GO:0048706 embryonic skeletal system development
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR020479 Homeodomain, metazoa
PFAM PF00046
PRINTS PR00024
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P09630
PhosphoSite PhosphoSite-P09630
TrEMBL D6RBH4
UniProt Splice Variant
Entrez Gene 3223
UniGene Hs.735752
RefSeq NP_004494
HUGO HGNC:5128
OMIM 142972
CCDS CCDS8871
HPRD 00858
IMGT
EMBL AC012531 AK314829 BC074844 BC074845 CH471054 M16938 S82986
GenPept AAA36007 AAB46892 AAH74844 AAH74845 BAG37349 EAW96746