Version 5.4
Homo sapiens Protein: CCR3
Summary
InnateDB Protein IDBP-374477.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCR3
Protein Name chemokine (C-C motif) receptor 3
Synonyms CC-CKR-3; CD193; CKR3; CMKBR3;
Species Homo sapiens
Ensembl Protein ENSP00000389336
InnateDB Gene IDBG-30125 (CCR3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 27 [view]
Protein-Protein 23 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0006954 inflammatory response
GO:0007186 G-protein coupled receptor signaling pathway
GO:0045087 innate immune response (InnateDB)
GO:0070098 chemokine-mediated signaling pathway
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000355 Chemokine receptor family
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00237
PR00657
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q96T97
UniProt Splice Variant
Entrez Gene 1232
UniGene Hs.730136
RefSeq
HUGO HGNC:1604
OMIM 601268
CCDS
HPRD 03167
IMGT
EMBL AC104439 AF224495 AF262299 AF262302 AF262303 AH010691
GenPept AAK49027 AAK49028 AAL85628 AAL85631 AAL85632

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca