Version 5.4
Homo sapiens Protein: HSD17B4
Summary
InnateDB Protein IDBP-375158.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSD17B4
Protein Name hydroxysteroid (17-beta) dehydrogenase 4
Synonyms DBP; MFE-2; MPF-2; PRLTS1; SDR8C1;
Species Homo sapiens
Ensembl Protein ENSP00000390208
InnateDB Gene IDBG-38417 (HSD17B4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 33 [view]
Protein-Protein 28 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
Biological Process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR002198 Short-chain dehydrogenase/reductase SDR
IPR002347 Glucose/ribitol dehydrogenase
IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
IPR013968 Polyketide synthase, KR
IPR020842 Polyketide synthase/Fatty acid synthase, KR
IPR029069 HotDog domain
PFAM PF00106
PF08659
PRINTS PR00080
PR00081
PR01397
PIRSF PIRSF000126
SMART SM00822
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9UBA4
UniProt Splice Variant
Entrez Gene 3295
UniGene
RefSeq
HUGO HGNC:5213
OMIM 601860
CCDS
HPRD 03514
IMGT
EMBL AC010409 AC024564 Y11393
GenPept CAA72203

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca