Version 5.4
Homo sapiens Protein: B3GALT4
Summary
InnateDB Protein IDBP-375446.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol B3GALT4
Protein Name UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
Synonyms BETA3GALT4; GALT2; GALT4;
Species Homo sapiens
Ensembl Protein ENSP00000390784
InnateDB Gene IDBG-304157 (B3GALT4)
Protein Structure
UniProt Annotation
Function Involved in GM1/GD1B/GA1 ganglioside biosynthesis. {ECO:0000269PubMed:9582303}.
Subcellular Localization Golgi apparatus membrane; Single-pass type II membrane protein.
Disease Associations
Tissue Specificity Highly expressed in heart, skeletal muscle and pancreas and, to a lesser extent, in brain, placenta, kidney, liver and lung. {ECO:0000269PubMed:10663566, ECO:0000269PubMed:9582303}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008378 galactosyltransferase activity
GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
GO:0047915 ganglioside galactosyltransferase activity
Biological Process
GO:0006486 protein glycosylation
Cellular Component
GO:0000139 Golgi membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002659 Glycosyl transferase, family 31
PFAM PF01762
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O96024
PhosphoSite PhosphoSite-O96024
TrEMBL Q5STJ7
UniProt Splice Variant
Entrez Gene 8705
UniGene Hs.534375
RefSeq NP_003773
HUGO HGNC:919
OMIM 603095
CCDS CCDS34425
HPRD 04370
IMGT
EMBL AB026730 AK315647 AL031228 BC032574 CH471081 CR457093 FJ525877 Y15061
GenPept AAH32574 ACN81315 BAA88988 BAG38014 CAA20230 CAA75345 CAG33374 EAX03700

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca